An age-structured model for coupling within-host and between-host dynamics in environmentally-driven infectious diseases
نویسندگان
چکیده
منابع مشابه
A mathematical model for coupling within-host and between-host dynamics in an environmentally-driven infectious disease.
This work presents a new model for the linking of within- and between-host dynamics. We use this as a conceptual model for the dynamics of Toxoplasma gondii, in which the parasite's life cycle includes interactions with the environment. We postulate the infection process to depend on the size of the infective inoculum that susceptible hosts may acquire by interacting with a contaminated environ...
متن کاملCoupling Within-Host and Between-Host Infectious Diseases Models
Biological processes occur at distinct but interlinked scales of organization. Yet, mathematical models are often focused on a single scale. Recently, there has been a significant interest in creating and using models that link the withinhost dynamics and population level dynamics of infectious diseases. These types of multi-scale models, called immuno-epidemiological models, fall in four categ...
متن کاملA discrete-time analog for coupled within-host and between-host dynamics in environmentally driven infectious disease
In this paper, we establish a discrete-time analog for coupled within-host and between-host systems for an environmentally driven infectious disease with fast and slow two time scales by using the non-standard finite difference scheme. The system is divided into a fast time system and a slow time system by using the idea of limit equations. For the fast system, the positivity and boundedness of...
متن کاملAn Age-Structured Within-Host Model for Multistrain Malaria Infections
In this paper we propose an age-structured malaria within-host model taking into account multi-strains interaction. We provide a global analysis of the model depending upon some threshold T0. When T0 ≤ 1, then the disease free equilibrium is globally asymptotically stable and the parasites are cleared. On the contrary if T0 > 1, the model exhibits the competition exclusion principle. Roughly sp...
متن کاملEmerging disease dynamics in a model coupling within-host and between-host systems.
Epidemiological models and immunological models have been studied largely independently. However, the two processes (between- and within-host interactions) occur jointly and models that couple the two processes may generate new biological insights. Particularly, the threshold conditions for disease control may be dramatically different when compared with those generated from the epidemiological...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chaos, Solitons & Fractals
سال: 2020
ISSN: 0960-0779
DOI: 10.1016/j.chaos.2020.110024